Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882

Polysaccharide produced from medicinal endophytic fungus not only has applications in foods, but also exhibits multiple biological activities. In this work, an endophytic fungus Chaetomium globosum CGMCC 6882 could use corn stover to produce a polysaccharide (GCP-SC) by consolidated bioprocess and t...

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Main Authors:	Lin Peng, Tao Ning, Wenbo Lu, Peizhang Chen, Haifeng Li, Yanjie Yi, Zichao Wang, Yuansen Hu
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2019-03-01
Series:	Grain & Oil Science and Technology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590259819300019

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spelling	doaj-62f6b4155ae64b93b175243500ebded52021-02-02T07:24:41ZengKeAi Communications Co., Ltd.Grain & Oil Science and Technology2590-25982019-03-01211114Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882Lin Peng0Tao Ning1Wenbo Lu2Peizhang Chen3Haifeng Li4Yanjie Yi5Zichao Wang6Yuansen Hu7National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China; Corresponding authors.College of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China; Corresponding authors.Polysaccharide produced from medicinal endophytic fungus not only has applications in foods, but also exhibits multiple biological activities. In this work, an endophytic fungus Chaetomium globosum CGMCC 6882 could use corn stover to produce a polysaccharide (GCP-SC) by consolidated bioprocess and the titer of GCP-SC reached 3.2 g/L. The transcriptional levels of genes related to cellulose degradation (cbh, cdh, glu and egl) in C. globosum CGMCC 6882 were 4.38, 3.85, 3.13, and 2.17 folds compared to the control group when corn stover was used as the sole carbon source. Moreover, GCP-SC showed a time- and dose-dependent manner of inhibitory effect on A549 cells and the inhibitory rate reached 93.3%. This work provides meaningful data on agricultural residues utilization and facilitation of future relative resource conversion studies. Keywords: Corn stover, Chaetomium globosum CGMCC 6882, Polysaccharidehttp://www.sciencedirect.com/science/article/pii/S2590259819300019
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Lin Peng Tao Ning Wenbo Lu Peizhang Chen Haifeng Li Yanjie Yi Zichao Wang Yuansen Hu
spellingShingle	Lin Peng Tao Ning Wenbo Lu Peizhang Chen Haifeng Li Yanjie Yi Zichao Wang Yuansen Hu Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882 Grain & Oil Science and Technology
author_facet	Lin Peng Tao Ning Wenbo Lu Peizhang Chen Haifeng Li Yanjie Yi Zichao Wang Yuansen Hu
author_sort	Lin Peng
title	Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882
title_short	Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882
title_full	Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882
title_fullStr	Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882
title_full_unstemmed	Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882
title_sort	consolidated bioprocess of corn stover to polysaccharide using chaetomium globosum cgmcc 6882
publisher	KeAi Communications Co., Ltd.
series	Grain & Oil Science and Technology
issn	2590-2598
publishDate	2019-03-01
description	Polysaccharide produced from medicinal endophytic fungus not only has applications in foods, but also exhibits multiple biological activities. In this work, an endophytic fungus Chaetomium globosum CGMCC 6882 could use corn stover to produce a polysaccharide (GCP-SC) by consolidated bioprocess and the titer of GCP-SC reached 3.2 g/L. The transcriptional levels of genes related to cellulose degradation (cbh, cdh, glu and egl) in C. globosum CGMCC 6882 were 4.38, 3.85, 3.13, and 2.17 folds compared to the control group when corn stover was used as the sole carbon source. Moreover, GCP-SC showed a time- and dose-dependent manner of inhibitory effect on A549 cells and the inhibitory rate reached 93.3%. This work provides meaningful data on agricultural residues utilization and facilitation of future relative resource conversion studies. Keywords: Corn stover, Chaetomium globosum CGMCC 6882, Polysaccharide
url	http://www.sciencedirect.com/science/article/pii/S2590259819300019
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Consolidated bioprocess of corn stover to polysaccharide using Chaetomium globosum CGMCC 6882

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