Human Disease Insight: An integrated knowledge-based platform for disease-gene-drug information

• Main Authors: Munazzah Tasleem, Romana Ishrat, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan
• Format: Article
• Language: English
• Published: Elsevier 2016-05-01
• Series: Journal of Infection and Public Health
• Online Access: http://www.sciencedirect.com/science/article/pii/S1876034115002026

Summary: The scope of the Human Disease Insight (HDI) database is not limited to researchers or physicians as it also provides basic information to non-professionals and creates disease awareness, thereby reducing the chances of patient suffering due to ignorance. HDI is a knowledge-based resource providing information on human diseases to both scientists and the general public. Here, our mission is to provide a comprehensive human disease database containing most of the available useful information, with extensive cross-referencing. HDI is a knowledge management system that acts as a central hub to access information about human diseases and associated drugs and genes. In addition, HDI contains well-classified bioinformatics tools with helpful descriptions. These integrated bioinformatics tools enable researchers to annotate disease-specific genes and perform protein analysis, search for biomarkers and identify potential vaccine candidates. Eventually, these tools will facilitate the analysis of disease-associated data. The HDI provides two types of search capabilities and includes provisions for downloading, uploading and searching disease/gene/drug-related information. The logistical design of the HDI allows for regular updating. The database is designed to work best with Mozilla Firefox and Google Chrome and is freely accessible at http://humandiseaseinsight.com. Keywords: Human disease database, Human genome project, Data integration, Knowledge management system, Relational database management system