Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells

Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells

Abstract Background Due to their ability to limitlessly proliferate and specialize into almost any cell type, human induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to generate human brain microvascular endothelial cells (BMECs), which compose the blood–brain barrier (BBB),...

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Bibliographic Details
Main Authors: Emma K. Hollmann, Amanda K. Bailey, Archit V. Potharazu, M. Diana Neely, Aaron B. Bowman, Ethan S. Lippmann
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Induced pluripotent stem cells (iPSCs)
In vitro blood–brain barrier (BBB) model
Brain microvascular endothelial cells (BMECs)
Defined differentiation medium
Online Access:http://link.springer.com/article/10.1186/s12987-017-0059-0

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