Sensitive Detection of Nucleic Acids Using Subzyme Feedback Cascades
The development of Subzymes demonstrates how the catalytic activity of DNAzymes can be controlled for detecting nucleic acids; however, Subzymes alone lack the sensitivity required to detect low target concentrations. To improve sensitivity, we developed a feedback system using a pair of cross-catal...
Main Authors: | Nicole Hasick, Andrea Lawrence, Radhika Ramadas, Alison Todd |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/7/1755 |
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