Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer

Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer

Cannabinoids exhibit anti-inflammatory and antitumorigenic properties. Contrary to most cannabinoids present in the Cannabis plant, some, such as O-1602 and abnormal cannabidiol, have no or only little affinity to the CB1 or CB2 cannabinoid receptors and instead exert their effects through other rec...

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Bibliographic Details
Main Authors: Andrea Tomko, Lauren O’Leary, Hilary Trask, John C. Achenbach, Steven R. Hall, Kerry B. Goralski, Lee D. Ellis, Denis J. Dupré
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
cannabinoid
taxol
paclitaxel
breast cancer
apoptosis
cell migration
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01124/full

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