Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis
Ulcerative colitis (UC) is a type of chronic inflammatory recurrent disease. At present, the etiology and pathogenesis are still unclear, and immune factors are usually considered to be the final link in the pathogenesis of UC. Due to the increasing incidence of this disease, longer course of dis...
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doaj-63803f3a37e14eea998f979eeec857852021-05-10T03:50:32ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372021-04-012776166Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitisJiao-Jiao Zhang0Yi Li1Shaanxi University of Traditional Chinese Medicine, Shanxi, Xi’an 712046, ChinaShaanxi University of Traditional Chinese Medicine, Shanxi, Xi’an 712046, ChinaUlcerative colitis (UC) is a type of chronic inflammatory recurrent disease. At present, the etiology and pathogenesis are still unclear, and immune factors are usually considered to be the final link in the pathogenesis of UC. Due to the increasing incidence of this disease, longer course of disease, and difficult to heal, related research has gradually deepened, and related researches on intestinal flora, immunity, genetics, etc. have become hotspots. A large amount of evidence indicates that regulatory T cells (Treg), helper T cell 17 (Th17), Th17/ Treg immune axis and intestinal microbiota in UC patients play an important role in regulating the occurrence and development of diseases. In recent years, the intestine has been gradually discovered There is also a certain correlation between the tract microbiota and the Th17/ Treg immune axis. Therefore, this article examines a large number of relevant Chinese and English materials at home and abroad in recent years to analyze the Th17/Treg cells, intestinal microbiota and the relationship between the two in UC patients. The existing relevance and other issues are briefly discussed and summarized in order to provide more practical basis for clinical targeted therapy.http://www.hnykdxxb.com/PDF/202107/12.pdfulcerative colitisth17/tregintestinal flora |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jiao-Jiao Zhang Yi Li |
spellingShingle |
Jiao-Jiao Zhang Yi Li Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis Journal of Hainan Medical University ulcerative colitis th17/treg intestinal flora |
author_facet |
Jiao-Jiao Zhang Yi Li |
author_sort |
Jiao-Jiao Zhang |
title |
Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis |
title_short |
Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis |
title_full |
Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis |
title_fullStr |
Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis |
title_full_unstemmed |
Mechanism of Th17/Treg immune axis regulating the intestinal microflora of ulcerative colitis |
title_sort |
mechanism of th17/treg immune axis regulating the intestinal microflora of ulcerative colitis |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2021-04-01 |
description |
Ulcerative colitis (UC) is a type of chronic inflammatory recurrent disease. At present, the
etiology and pathogenesis are still unclear, and immune factors are usually considered to
be the final link in the pathogenesis of UC. Due to the increasing incidence of this disease,
longer course of disease, and difficult to heal, related research has gradually deepened, and
related researches on intestinal flora, immunity, genetics, etc. have become hotspots. A large
amount of evidence indicates that regulatory T cells (Treg), helper T cell 17 (Th17), Th17/
Treg immune axis and intestinal microbiota in UC patients play an important role in regulating
the occurrence and development of diseases. In recent years, the intestine has been gradually
discovered There is also a certain correlation between the tract microbiota and the Th17/
Treg immune axis. Therefore, this article examines a large number of relevant Chinese and
English materials at home and abroad in recent years to analyze the Th17/Treg cells, intestinal
microbiota and the relationship between the two in UC patients. The existing relevance and
other issues are briefly discussed and summarized in order to provide more practical basis for
clinical targeted therapy. |
topic |
ulcerative colitis th17/treg intestinal flora |
url |
http://www.hnykdxxb.com/PDF/202107/12.pdf |
work_keys_str_mv |
AT jiaojiaozhang mechanismofth17tregimmuneaxisregulatingtheintestinalmicrofloraofulcerativecolitis AT yili mechanismofth17tregimmuneaxisregulatingtheintestinalmicrofloraofulcerativecolitis |
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