Effects of sub-Tenon’s triamcinolone injections in patients with uveitis
ABSTRACT Purpose: To evaluate the response to sub-Tenon’s triamcinolone injection in patients with uveitis. Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon’s injection of triamcinolone and followed the patients for 180 days to analyze th...
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Conselho Brasileiro de Oftalmologia
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doaj-6382238feaa04615a9262769874c6a6c2020-11-25T00:44:41ZengConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia1678-292581432332910.5935/0004-2749.20180063S0004-27492018000400323Effects of sub-Tenon’s triamcinolone injections in patients with uveitisBianca Gubiani FerreiraDiane Ruschel MarinhoFelipe Teloken DiligentiABSTRACT Purpose: To evaluate the response to sub-Tenon’s triamcinolone injection in patients with uveitis. Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon’s injection of triamcinolone and followed the patients for 180 days to analyze the positive effects (improvement of macular edema and visual acuity) and monitor the possible adverse effects. This prospective study was conducted at the Department of Ophthalmology, Hospital de Clínicas de Porto Alegre, Brazil. Results: We observed improvement in macular edema in 86% of patients. The mean central macular thickness at each time point of assessment was 432.22, 298.80, 286.37, 267.49, 253.87, and 253.49 mm at baseline (before sub-Tenon’s injection of triamcinolone), 15 days after the procedure, at 30 days, at 60 days, at 90 days, and at 180 days, respectively. The mean reduction in retinal thickness was 30.8%, 33.7%, 38.11%, 41.2%, and 41.35% at 15, 30, 60, 90, and 180 days of follow-up, respectively. Visual acuity also improved in 85.7% of patients, with a mean improvement of 1.36, 1.93, 2.23, 2.26, and 2.30 lines gained on the Early Treatment Diabetic Retinopathy Study chart at 15, 30, 60, 90, and 180 days of follow-up, respectively. No statistically significant increases in intraocular pressure and conjunctival abnormalities were caused by the procedure, and no other adverse effects were observed. Overall, the results of this study were similar to those described in the literature. Conclusions: Sub-Tenon’s injection of triamcinolone provides reduced macular thickness and improvement in visual acuity with no significant adverse effects and is therefore an effective and safe procedure for the treatment of sequelae of uveitis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492018000400323&lng=en&tlng=enUveitisTriamcinoloneIntravitreal injectionsMacular edemaTenon capsuleVisual acuity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bianca Gubiani Ferreira Diane Ruschel Marinho Felipe Teloken Diligenti |
spellingShingle |
Bianca Gubiani Ferreira Diane Ruschel Marinho Felipe Teloken Diligenti Effects of sub-Tenon’s triamcinolone injections in patients with uveitis Arquivos Brasileiros de Oftalmologia Uveitis Triamcinolone Intravitreal injections Macular edema Tenon capsule Visual acuity |
author_facet |
Bianca Gubiani Ferreira Diane Ruschel Marinho Felipe Teloken Diligenti |
author_sort |
Bianca Gubiani Ferreira |
title |
Effects of sub-Tenon’s triamcinolone injections in patients with uveitis |
title_short |
Effects of sub-Tenon’s triamcinolone injections in patients with uveitis |
title_full |
Effects of sub-Tenon’s triamcinolone injections in patients with uveitis |
title_fullStr |
Effects of sub-Tenon’s triamcinolone injections in patients with uveitis |
title_full_unstemmed |
Effects of sub-Tenon’s triamcinolone injections in patients with uveitis |
title_sort |
effects of sub-tenon’s triamcinolone injections in patients with uveitis |
publisher |
Conselho Brasileiro de Oftalmologia |
series |
Arquivos Brasileiros de Oftalmologia |
issn |
1678-2925 |
description |
ABSTRACT Purpose: To evaluate the response to sub-Tenon’s triamcinolone injection in patients with uveitis. Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon’s injection of triamcinolone and followed the patients for 180 days to analyze the positive effects (improvement of macular edema and visual acuity) and monitor the possible adverse effects. This prospective study was conducted at the Department of Ophthalmology, Hospital de Clínicas de Porto Alegre, Brazil. Results: We observed improvement in macular edema in 86% of patients. The mean central macular thickness at each time point of assessment was 432.22, 298.80, 286.37, 267.49, 253.87, and 253.49 mm at baseline (before sub-Tenon’s injection of triamcinolone), 15 days after the procedure, at 30 days, at 60 days, at 90 days, and at 180 days, respectively. The mean reduction in retinal thickness was 30.8%, 33.7%, 38.11%, 41.2%, and 41.35% at 15, 30, 60, 90, and 180 days of follow-up, respectively. Visual acuity also improved in 85.7% of patients, with a mean improvement of 1.36, 1.93, 2.23, 2.26, and 2.30 lines gained on the Early Treatment Diabetic Retinopathy Study chart at 15, 30, 60, 90, and 180 days of follow-up, respectively. No statistically significant increases in intraocular pressure and conjunctival abnormalities were caused by the procedure, and no other adverse effects were observed. Overall, the results of this study were similar to those described in the literature. Conclusions: Sub-Tenon’s injection of triamcinolone provides reduced macular thickness and improvement in visual acuity with no significant adverse effects and is therefore an effective and safe procedure for the treatment of sequelae of uveitis. |
topic |
Uveitis Triamcinolone Intravitreal injections Macular edema Tenon capsule Visual acuity |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492018000400323&lng=en&tlng=en |
work_keys_str_mv |
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