İSOTRETİNOİN TEDAVİSİNİN NÖTROFİL/LENFOSİT ORANI VE DİĞER HEMOGRAM PARAMETRELERİNE ETKİSİNİN DEĞERLENDİRİLMESİ

• Main Authors: Pınar Özuğuz, Seval Kaçar, Serap Polat, Sena Ulu, Şemsettin Karaca
• Format: Article
• Language: English
• Published: Mustafa Kemal University 2015-03-01
• Series: Mustafa Kemal Üniversitesi Tıp Dergisi
• Subjects: -; Isotretinoin; hemogram parameters; hemoglobulin; neutrophil/lymphocyte ratio monocyte; eosinophil; Anahtar hemogram parametreleri; hemoglobin; monosit; nötrofil/lenfosit oranı kelimeler: Eozinofil; isotretinoin
• Online Access: http://dergipark.gov.tr/mkutfd/issue/19595/209351?publisher=mku
• ISSN: 2149-3103

Aim: There are reports of various side effects of isotretinoin. Recent studies have controversial results about the necessity of laboratory investigation including hemogram and blood chemistry of patients during the follow up periodon isotretinoin.We aimed to investigate the effects of isotretinoin on Neutrophil/lymhocyte ratio (NLR) a systemic inflammation marker and the other hemogram parameters. Material and methods: Sixty seven patients with moderate to severe acne vulgaris aged between 18 to 25, who were prescribed 0.5mg/kg isotretinoin, were included to the study. Patients’ hemogram parameters before treatment and at the third month of treatment were recorded on SPSS 20.0 programme retrospectively. The difference between two values