A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion

Summary: Metastasis is the leading cause of death for patients with cancer. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumor growth toward malignancy. Advances in genome characterization technologies have been very success...

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Main Authors: Brenda Canales Coutiño, Zoe E. Cornhill, Africa Couto, Natalie A. Mack, Alexandra D. Rusu, Usha Nagarajan, Yuen Ngan Fan, Marina R. Hadjicharalambous, Marcos Castellanos Uribe, Amy Burrows, Anbarasu Lourdusamy, Ruman Rahman, Sean T. May, Marios Georgiou
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304223