A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion
Summary: Metastasis is the leading cause of death for patients with cancer. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumor growth toward malignancy. Advances in genome characterization technologies have been very success...
Main Authors: | Brenda Canales Coutiño, Zoe E. Cornhill, Africa Couto, Natalie A. Mack, Alexandra D. Rusu, Usha Nagarajan, Yuen Ngan Fan, Marina R. Hadjicharalambous, Marcos Castellanos Uribe, Amy Burrows, Anbarasu Lourdusamy, Ruman Rahman, Sean T. May, Marios Georgiou |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220304223 |
Similar Items
-
CG7379 and ING1 suppress cancer cell invasion by maintaining cell–cell junction integrity
by: Alexandra D. Rusu, et al.
Published: (2021-09-01) -
Generation and live imaging of tumors with specific genotypes in the living fly pupa
by: Brenda Canales Coutiño, et al.
Published: (2021-09-01) -
Regulation of synaptonemal complex assembly through nuclear import and loading of cohesins and SYP-2 proteins in Caenorhabditis elegans
by: Bowman, Richard
Published: (2017) -
INVESTIGATION INTO THE MEIOTIC ROLES OF COHESIN AND CENTROMERE PROTEINS IN <i>CAENORHABDITIS ELEGANS</i>
by: Joswala, Swetha Ramani
Published: (2020) -
Genome-Wide Loss-of-Function Genetic Screens Identify Novel Senescence Genes and Putative Tumor Suppressors
by: Burrows, Anna
Published: (2013)