Nuclear Transfer Arrest Embryos Show Massive Dysregulation of Genes Involved in Transcription Pathways

Nuclear Transfer Arrest Embryos Show Massive Dysregulation of Genes Involved in Transcription Pathways

Somatic cell nuclear transfer (SCNT) technology can reprogram terminally differentiated cell nuclei into a totipotent state. However, the underlying molecular barriers of SCNT embryo development remain incompletely elucidated. Here, we observed that transcription-related pathways were incompletely a...

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Bibliographic Details
Main Authors: Chunshen Long, Hanshuang Li, Xinru Li, Wuritu Yang, Yongchun Zuo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
SCNT embryos
transcription pathways
gene regulatory networks
abnormal gene expression
molecular barriers
Online Access:https://www.mdpi.com/1422-0067/22/15/8187

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