Modulation of signal strength switches Notch from an inducer of T cells to an inducer of ILC2
Innate lymphoid cells (ILC) are emerging key players of the immune system with close lineage relationship to T cells. ILC2 play an important role in protective immunity against multicellular parasites, but are also involved in the pathogenesis of type 2 immune diseases. Here, we have studied the dev...
Main Authors: | Rebecca eGentek, J. Marius Munneke, Christina eHelbig, Bianca eBlom, Mette D Hazenberg, Hergen eSpits, Derk eAmsen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00334/full |
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