Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery
Abstract Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored to detect SV valves, tributaries, and vessel size employing upright computed tomog...
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2021-06-01
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Online Access: | https://doi.org/10.1038/s41598-021-90998-7 |
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doaj-63be87b63a2a4a2b9e0f1cc293cd1cba2021-06-06T11:39:46ZengNature Publishing GroupScientific Reports2045-23222021-06-011111810.1038/s41598-021-90998-7Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgeryTakehiro Nakahara0Minoru Yamada1Yoichi Yokoyama2Yoshitake Yamada3Keiichi Narita4Nobuaki Imanishi5Masataka Yamazaki6Hideyuki Shimizu7Jagat Narula8Masahiro Jinzaki9Department of Radiology, Keio University School of MedicineDepartment of Radiology, Keio University School of MedicineDepartment of Radiology, Keio University School of MedicineDepartment of Radiology, Keio University School of MedicineDepartment of Radiology, Keio University School of MedicineDepartment of Plastic and Reconstructive Surgery, Keio University School of MedicineDepartment of Cardiovascular Surgery, Keio University School of MedicineDepartment of Cardiovascular Surgery, Keio University School of MedicineMount Sinai Heart, Icahn School of Medicine at Mount SinaiDepartment of Radiology, Keio University School of MedicineAbstract Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored to detect SV valves, tributaries, and vessel size employing upright computed tomography (CT) for the raw cadaver venous samples and in healthy volunteers. Five cadaver legs were scanned. Anatomical analysis showed 3.0 (IQR: 2.0–3.0) valves and 13.50 (IQR: 10.00–16.25) tributaries. The upright CT completely detected, compared to 2.0 (IQR: 1.5–2.5, p = 0.06) valves and 9.5 (IQR: 7.5–13.0, p = 0.13) tributaries by supine CT. From a total of 190 volunteers, 138 (men:75, women:63) were included. The number of valves from the SF junction to 35 cm were significantly higher in upright CT than in supine CT bilaterally [upright vs. supine, Right: 4 (IQR: 3–5) vs. 2 (IQR:1–2), p < 0.0001, Left: 4 (IQR: 3–5) vs. 2 (IQR: 1–2), p < 0.0001]. The number of tributaries and vessel areas per leg were also higher for upright compared with supine CT. Upright CT enables non-invasive detection of SV valves, tributaries, and vessel size. Although not tested here, it is expected that upright CT may potentially improve graft assessment for bypass surgery.https://doi.org/10.1038/s41598-021-90998-7 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Takehiro Nakahara Minoru Yamada Yoichi Yokoyama Yoshitake Yamada Keiichi Narita Nobuaki Imanishi Masataka Yamazaki Hideyuki Shimizu Jagat Narula Masahiro Jinzaki |
spellingShingle |
Takehiro Nakahara Minoru Yamada Yoichi Yokoyama Yoshitake Yamada Keiichi Narita Nobuaki Imanishi Masataka Yamazaki Hideyuki Shimizu Jagat Narula Masahiro Jinzaki Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery Scientific Reports |
author_facet |
Takehiro Nakahara Minoru Yamada Yoichi Yokoyama Yoshitake Yamada Keiichi Narita Nobuaki Imanishi Masataka Yamazaki Hideyuki Shimizu Jagat Narula Masahiro Jinzaki |
author_sort |
Takehiro Nakahara |
title |
Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery |
title_short |
Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery |
title_full |
Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery |
title_fullStr |
Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery |
title_full_unstemmed |
Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery |
title_sort |
saphenous vein valve assessment utilizing upright ct to potentially improve graft assessment for bypass surgery |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-06-01 |
description |
Abstract Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored to detect SV valves, tributaries, and vessel size employing upright computed tomography (CT) for the raw cadaver venous samples and in healthy volunteers. Five cadaver legs were scanned. Anatomical analysis showed 3.0 (IQR: 2.0–3.0) valves and 13.50 (IQR: 10.00–16.25) tributaries. The upright CT completely detected, compared to 2.0 (IQR: 1.5–2.5, p = 0.06) valves and 9.5 (IQR: 7.5–13.0, p = 0.13) tributaries by supine CT. From a total of 190 volunteers, 138 (men:75, women:63) were included. The number of valves from the SF junction to 35 cm were significantly higher in upright CT than in supine CT bilaterally [upright vs. supine, Right: 4 (IQR: 3–5) vs. 2 (IQR:1–2), p < 0.0001, Left: 4 (IQR: 3–5) vs. 2 (IQR: 1–2), p < 0.0001]. The number of tributaries and vessel areas per leg were also higher for upright compared with supine CT. Upright CT enables non-invasive detection of SV valves, tributaries, and vessel size. Although not tested here, it is expected that upright CT may potentially improve graft assessment for bypass surgery. |
url |
https://doi.org/10.1038/s41598-021-90998-7 |
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