The Effect of Candesartan Alone and Its Combination With Estrogen on Post-traumatic Brain Injury Outcomes in Female Rats

The Effect of Candesartan Alone and Its Combination With Estrogen on Post-traumatic Brain Injury Outcomes in Female Rats

Aim: The aim of this study was to evaluate the effect of candesartan (angiotensin II type I receptor blocker) alone and its combination with estrogen on the changes in brain edema, intracranial pressure (ICP), and cerebral perfusion pressure (CPP) following diffuse traumatic brain injury (TBI) in fe...

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Bibliographic Details
Main Authors: Mojdeh Hajmohammadi, Mohammad Khaksari, Zahra Soltani, Nader Shahrokhi, Hamid Najafipour, Reza Abbasi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
candesartan
estrogen
intracranial pressure
cerebral perfusion pressure
brain edema
mean arterial pressure
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01043/full

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