The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait....
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2014-03-01
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doaj-63c94a3439f24d6d92aeeaed7985c52c2020-11-24T21:39:01ZengElsevierJournal of Infection and Public Health1876-03412014-03-017299105The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-reviewPrashant Purohit0Ina’am Ahmad Al-Obaid1Nehad Gamal Al-Deen Omar2Department of Microbiology, Al-Sabah Hospital, Kuwait; Corresponding author at: Post Box 1359, Al-Ardiya 92400, Kuwait. Tel.: +965 22273132; fax: +965 24818541; mobile: +965 66069347.Department of Microbiology, Al-Sabah Hospital, KuwaitDepartment of Paediatrics, Al-Sabah Hospital, KuwaitSummary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait. This report examines the possible reasons for this failure by reviewing the literature and emphasizes the need to broaden the definition of vaccine failure with the aim of optimizing the timing of the vaccine booster dose for prematurely born children and establishing continuous surveillance for Hib vaccine failure. Keywords: Haemophilus influenzae type b vaccine failure, Haemophilus influenzae type b meningitishttp://www.sciencedirect.com/science/article/pii/S1876034113001317 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Prashant Purohit Ina’am Ahmad Al-Obaid Nehad Gamal Al-Deen Omar |
spellingShingle |
Prashant Purohit Ina’am Ahmad Al-Obaid Nehad Gamal Al-Deen Omar The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review Journal of Infection and Public Health |
author_facet |
Prashant Purohit Ina’am Ahmad Al-Obaid Nehad Gamal Al-Deen Omar |
author_sort |
Prashant Purohit |
title |
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review |
title_short |
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review |
title_full |
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review |
title_fullStr |
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review |
title_full_unstemmed |
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review |
title_sort |
first reported case of possible haemophilus influenzae type b vaccine failure from kuwait and literature-review |
publisher |
Elsevier |
series |
Journal of Infection and Public Health |
issn |
1876-0341 |
publishDate |
2014-03-01 |
description |
Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait. This report examines the possible reasons for this failure by reviewing the literature and emphasizes the need to broaden the definition of vaccine failure with the aim of optimizing the timing of the vaccine booster dose for prematurely born children and establishing continuous surveillance for Hib vaccine failure. Keywords: Haemophilus influenzae type b vaccine failure, Haemophilus influenzae type b meningitis |
url |
http://www.sciencedirect.com/science/article/pii/S1876034113001317 |
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