The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review

The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review

Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait....

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Main Authors: Prashant Purohit, Ina’am Ahmad Al-Obaid, Nehad Gamal Al-Deen Omar
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034113001317
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spelling doaj-63c94a3439f24d6d92aeeaed7985c52c2020-11-24T21:39:01ZengElsevierJournal of Infection and Public Health1876-03412014-03-017299105The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-reviewPrashant Purohit0Ina’am Ahmad Al-Obaid1Nehad Gamal Al-Deen Omar2Department of Microbiology, Al-Sabah Hospital, Kuwait; Corresponding author at: Post Box 1359, Al-Ardiya 92400, Kuwait. Tel.: +965 22273132; fax: +965 24818541; mobile: +965 66069347.Department of Microbiology, Al-Sabah Hospital, KuwaitDepartment of Paediatrics, Al-Sabah Hospital, KuwaitSummary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait. This report examines the possible reasons for this failure by reviewing the literature and emphasizes the need to broaden the definition of vaccine failure with the aim of optimizing the timing of the vaccine booster dose for prematurely born children and establishing continuous surveillance for Hib vaccine failure. Keywords: Haemophilus influenzae type b vaccine failure, Haemophilus influenzae type b meningitishttp://www.sciencedirect.com/science/article/pii/S1876034113001317
collection DOAJ
language English
format Article
sources DOAJ
author Prashant Purohit
Ina’am Ahmad Al-Obaid
Nehad Gamal Al-Deen Omar
spellingShingle Prashant Purohit
Ina’am Ahmad Al-Obaid
Nehad Gamal Al-Deen Omar
The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
Journal of Infection and Public Health
author_facet Prashant Purohit
Ina’am Ahmad Al-Obaid
Nehad Gamal Al-Deen Omar
author_sort Prashant Purohit
title The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
title_short The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
title_full The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
title_fullStr The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
title_full_unstemmed The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review
title_sort first reported case of possible haemophilus influenzae type b vaccine failure from kuwait and literature-review
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2014-03-01
description Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture. This case represents the first report of possible Hib vaccine failure from Kuwait. This report examines the possible reasons for this failure by reviewing the literature and emphasizes the need to broaden the definition of vaccine failure with the aim of optimizing the timing of the vaccine booster dose for prematurely born children and establishing continuous surveillance for Hib vaccine failure. Keywords: Haemophilus influenzae type b vaccine failure, Haemophilus influenzae type b meningitis
url http://www.sciencedirect.com/science/article/pii/S1876034113001317
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