OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS

This study reports the optimization of geranyl butanoate production by esterification of geraniol and butanoic acid in a solvent-free system using two immobilized lipases as catalyst. The operating conditions that optimized geranyl butanoate production were determined to be 40 °C, a geraniol to buta...

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Main Authors: Carla R. Sbardelotto, Suelen P. Piazza, Nadia L. D. Nyari, Rogério M. Dallago, Débora de Oliveira, Vladimir de Oliveira, Jamile Zeni, Rogério L. Cansian, Natalia Paroul
Format: Article
Language:English
Published: Sociedade Brasileira de Química
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000800905&lng=en&tlng=en
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spelling doaj-63dda7beeddd459d9ab9b39e0e745c582020-11-24T22:14:51ZengSociedade Brasileira de QuímicaQuímica Nova1678-706441890591110.21577/0100-4042.20170259S0100-40422018000800905OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTSCarla R. SbardelottoSuelen P. PiazzaNadia L. D. NyariRogério M. DallagoDébora de OliveiraVladimir de OliveiraJamile ZeniRogério L. CansianNatalia ParoulThis study reports the optimization of geranyl butanoate production by esterification of geraniol and butanoic acid in a solvent-free system using two immobilized lipases as catalyst. The operating conditions that optimized geranyl butanoate production were determined to be 40 °C, a geraniol to butanoic acid molar ratio of 3:1, 150 rpm, 5 wt% of enzyme, and 1 h of reaction, which resulted in a reaction conversion of about 97% for Novozyme 435. When homemade Novozyme NZL-102-LYO-HQ (Cal-B) immobilized in polyurethane foam was used as catalyst, the experimental conditions of an alcohol to acid molar ratio of 5:1, 70 °C, 150 rpm, 5 wt% of enzyme, and 1 h of reaction gave a conversion of 95%. New experimental data on enzymatic esterification of geraniol and butanoic acid for geranyl butanoate production are reported in this work, showing that the technique is promising for overcoming the well-known drawbacks of the chemical-catalyzed route.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000800905&lng=en&tlng=enesterificationgeranyl butanoateNovozyme 435Novozyme NZL-102-LYO-HQ
collection DOAJ
language English
format Article
sources DOAJ
author Carla R. Sbardelotto
Suelen P. Piazza
Nadia L. D. Nyari
Rogério M. Dallago
Débora de Oliveira
Vladimir de Oliveira
Jamile Zeni
Rogério L. Cansian
Natalia Paroul
spellingShingle Carla R. Sbardelotto
Suelen P. Piazza
Nadia L. D. Nyari
Rogério M. Dallago
Débora de Oliveira
Vladimir de Oliveira
Jamile Zeni
Rogério L. Cansian
Natalia Paroul
OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
Química Nova
esterification
geranyl butanoate
Novozyme 435
Novozyme NZL-102-LYO-HQ
author_facet Carla R. Sbardelotto
Suelen P. Piazza
Nadia L. D. Nyari
Rogério M. Dallago
Débora de Oliveira
Vladimir de Oliveira
Jamile Zeni
Rogério L. Cansian
Natalia Paroul
author_sort Carla R. Sbardelotto
title OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
title_short OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
title_full OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
title_fullStr OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
title_full_unstemmed OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS
title_sort optimization of solvent-free geranyl butanoate production using novozyme 435 and homemade polyurethane immobilized novozyme nzl-102-lyo-hq as catalysts
publisher Sociedade Brasileira de Química
series Química Nova
issn 1678-7064
description This study reports the optimization of geranyl butanoate production by esterification of geraniol and butanoic acid in a solvent-free system using two immobilized lipases as catalyst. The operating conditions that optimized geranyl butanoate production were determined to be 40 °C, a geraniol to butanoic acid molar ratio of 3:1, 150 rpm, 5 wt% of enzyme, and 1 h of reaction, which resulted in a reaction conversion of about 97% for Novozyme 435. When homemade Novozyme NZL-102-LYO-HQ (Cal-B) immobilized in polyurethane foam was used as catalyst, the experimental conditions of an alcohol to acid molar ratio of 5:1, 70 °C, 150 rpm, 5 wt% of enzyme, and 1 h of reaction gave a conversion of 95%. New experimental data on enzymatic esterification of geraniol and butanoic acid for geranyl butanoate production are reported in this work, showing that the technique is promising for overcoming the well-known drawbacks of the chemical-catalyzed route.
topic esterification
geranyl butanoate
Novozyme 435
Novozyme NZL-102-LYO-HQ
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000800905&lng=en&tlng=en
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