Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis.
Methamphetamine is a highly addictive psychostimulant that causes profound damage to the brain and other body organs. Post mortem studies of human tissues have linked the use of this drug to diseases associated with aging, such as coronary atherosclerosis and pulmonary fibrosis, but the molecular me...
Main Authors: | Giuseppe Astarita, Agnesa Avanesian, Benedetto Grimaldi, Natalia Realini, Zuzana Justinova, Leight V Panlilio, Abdul Basit, Steven R Goldberg, Daniele Piomelli |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4324822?pdf=render |
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