Long-term use of dipeptyl peptidase-4 inhibitors suppresses systemic oxidative stress in rats with type 2 diabetes

Long-term use of dipeptyl peptidase-4 inhibitors suppresses systemic oxidative stress in rats with type 2 diabetes

Induction of oxidative stress is one of the main mechanisms responsible for the development of micro- and macrovascular angiopathy in patients with type 2 diabetes mellitus (DM-2).Aim. To evaluate the influence of long-term treatment with inhibitors of dipeptidyl peptidase-4 (DPP-4) on the characteri...

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Bibliographic Details
Main Authors: S. S. Bolevich, P. F. Litvitsky, V. Jakovljevic, S. B. Bolevich
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2019-12-01
Series:Сеченовский вестник
Subjects:
type 2 diabetes mellitus
saxagliptine
sitagliptine
vildagliptine
oxidative stress
antioxidant defensive system
Online Access:https://www.sechenovmedj.com/jour/article/view/179

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