The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis
Objective: To analyse the diagnostic performance of endometrial volume calculated by three-dimensional (3D) ultrasound for diagnosing endometrial carcinoma in women with postmenopausal bleeding. Methods: An extensive search of papers analysing the role of endometrial volume calculated by 3D ultra...
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European Medical Journal
2020-09-01
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doaj-6408c7ae5a4d4f7d885afb932b2cd7492021-02-09T15:57:01ZengEuropean Medical JournalEMJ Radiology2633-99782020-09-0111798810.33590/emjradiol/20-00049The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis Cristian Morales0Raul Diago1Salvador Cortés2Carla Peixoto3Maria Ángela Pascual4Stefano Guerriero5Juan Luis Alcázar6Department of Obstetrics and Gynecology, Hospital San Juan de Dios, Santiago, ChileDepartment of Obstetrics and Gynecology, Hospital Universitario Severo Ochoa, Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Virgen de la Arrixaca, Murcia, SpainDepartment of Obstetrics and Gynecology, Centro Hospitalar São João, Porto, PortugalDepartment of Obstetrics, Gynecology, and Reproduction, Hospital Universitario Dexeus, Barcelona, SpainDepartment of Obstetrics and Gynecology, Policlinico Universitario Duilio Casula, Cagliari, ItalyDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, Pamplona, SpainObjective: To analyse the diagnostic performance of endometrial volume calculated by three-dimensional (3D) ultrasound for diagnosing endometrial carcinoma in women with postmenopausal bleeding. Methods: An extensive search of papers analysing the role of endometrial volume calculated by 3D ultrasound for diagnosing endometrial carcinoma in women with postmenopausal bleeding was performed in MEDLINE/PubMed and Web of Science from January 1996 to January 2020. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool. Results: The extended search identified 318 citations but after exclusions, eight articles were included in the meta-analysis. The risk of bias for most studies was high for the four domains assessed in QUADAS-2. Overall, after excluding three studies that contributed significantly to heterogeneity, pooled estimated sensitivity and specificity for diagnosing endometrial cancer were 87% (95% confidence interval: 80–92%) and 60% (95% confidence interval: 51–68%), respectively. Heterogeneity was low or moderate. Conclusion: Endometrial volume as estimated by 3D ultrasound using virtual organ computer-aided analysis (VOCALTM) software has a moderate diagnostic performance for detecting endometrial malignancy in women with postmenopausal bleeding.https://www.emjreviews.com/radiology/article/the-value-of-endometrial-volume-as-estimated-by-three-dimensional-ultrasound-for-detecting-endometrial-cancer-in-postmenopausal-women-a-systematic-review-and-meta-analysis/cancerendometrialendometrial volumethree-dimensional (3d) ultrasound |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cristian Morales Raul Diago Salvador Cortés Carla Peixoto Maria Ángela Pascual Stefano Guerriero Juan Luis Alcázar |
spellingShingle |
Cristian Morales Raul Diago Salvador Cortés Carla Peixoto Maria Ángela Pascual Stefano Guerriero Juan Luis Alcázar The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis EMJ Radiology cancer endometrial endometrial volume three-dimensional (3d) ultrasound |
author_facet |
Cristian Morales Raul Diago Salvador Cortés Carla Peixoto Maria Ángela Pascual Stefano Guerriero Juan Luis Alcázar |
author_sort |
Cristian Morales |
title |
The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis |
title_short |
The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis |
title_full |
The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis |
title_fullStr |
The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis |
title_full_unstemmed |
The Value of Endometrial Volume as Estimated by Three-Dimensional Ultrasound for Detecting Endometrial Cancer in Postmenopausal Women: A Systematic Review and Meta-Analysis |
title_sort |
value of endometrial volume as estimated by three-dimensional ultrasound for detecting endometrial cancer in postmenopausal women: a systematic review and meta-analysis |
publisher |
European Medical Journal |
series |
EMJ Radiology |
issn |
2633-9978 |
publishDate |
2020-09-01 |
description |
Objective: To analyse the diagnostic performance of endometrial volume calculated by three-dimensional (3D) ultrasound for diagnosing endometrial carcinoma in women with postmenopausal bleeding.
Methods: An extensive search of papers analysing the role of endometrial volume calculated by 3D ultrasound for diagnosing endometrial carcinoma in women with postmenopausal bleeding was performed in MEDLINE/PubMed and Web of Science from January 1996 to January 2020. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool.
Results: The extended search identified 318 citations but after exclusions, eight articles were
included in the meta-analysis. The risk of bias for most studies was high for the four domains assessed in QUADAS-2. Overall, after excluding three studies that contributed significantly to heterogeneity, pooled estimated sensitivity and specificity for diagnosing endometrial cancer were 87% (95% confidence interval: 80–92%) and 60% (95% confidence interval: 51–68%), respectively. Heterogeneity was low or moderate.
Conclusion: Endometrial volume as estimated by 3D ultrasound using virtual organ computer-aided analysis (VOCALTM) software has a moderate diagnostic performance for detecting endometrial malignancy in women with postmenopausal bleeding. |
topic |
cancer endometrial endometrial volume three-dimensional (3d) ultrasound |
url |
https://www.emjreviews.com/radiology/article/the-value-of-endometrial-volume-as-estimated-by-three-dimensional-ultrasound-for-detecting-endometrial-cancer-in-postmenopausal-women-a-systematic-review-and-meta-analysis/ |
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