Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis
Abstract Background Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficiency virus (HIV) is one of the major public health problems associated wit...
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doaj-6411f8fa19d947789b8ff5431db4372f2020-11-25T04:04:35ZengBMCBMC Infectious Diseases1471-23342019-05-011911910.1186/s12879-019-4012-5Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysisHenok Mulugeta0Getenet Dessie1Fasil Wagnew2Dube Jara3Cheru Tesema Leshargie4Ayenew Negesse5Department of Nursing, College of Health Science, Debre Markos UniversityDepartment of Nursing, School of health science, College of Medicine and Health Science, Bahir Dar UniversityDepartment of Nursing, College of Health Science, Debre Markos UniversityDepartment of Public Health, College of Health Science, Debre Markos UniversityDepartment of Environmental Health, College of Health Science, Debre Markos UniversityDepartment of Human nutrition and food science, College of Health Science, Debre Markos UniversityAbstract Background Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficiency virus (HIV) is one of the major public health problems associated with blood transfusion. The objective of this systematic review and meta-analysis is to estimate seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia. Methods Studies on the prevalence of human immunodeficiency virus among blood donors published until 2017 were accessed by conducting a detailed search on PubMed, Cochrane Library, Google Scholar, EMBASE and CINAHL databases using the keywords:-“Seroprevalence” AND “trend” AND “HIV” OR “human” AND “immunodeficiency” AND “virus” OR “human immunodeficiency virus” AND “blood donors” OR “blood donors” OR “Ethiopia”. The quality of each article was assessed using a modified version of the Newcastle-Ottawa Scale. Meta-analysis was carried out using a random-effects method. All statistical analyses were done using STATA version 11 software. Result The estimated pooled seroprevalence of human immunodeficiency virus among blood donors in Ethiopia was 2.69% (95% CI (1.79–3.58%)). The overall seroprevalence of human immunodeficiency virus infection showed a significant decline trend from 2004 to 2016. Conclusion The overall seroprevalence of human immunodeficiency virus among blood donors in Ethiopia was high. Routine screening of donor blood for transfusion-transmissible infections is essential for ensuring the safety of blood transfusion.http://link.springer.com/article/10.1186/s12879-019-4012-5Blood donorHuman immunodeficiency virusSeroprevalenceEthiopia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Henok Mulugeta Getenet Dessie Fasil Wagnew Dube Jara Cheru Tesema Leshargie Ayenew Negesse |
spellingShingle |
Henok Mulugeta Getenet Dessie Fasil Wagnew Dube Jara Cheru Tesema Leshargie Ayenew Negesse Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis BMC Infectious Diseases Blood donor Human immunodeficiency virus Seroprevalence Ethiopia |
author_facet |
Henok Mulugeta Getenet Dessie Fasil Wagnew Dube Jara Cheru Tesema Leshargie Ayenew Negesse |
author_sort |
Henok Mulugeta |
title |
Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis |
title_short |
Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis |
title_full |
Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis |
title_fullStr |
Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis |
title_full_unstemmed |
Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis |
title_sort |
seroprevalence and trend of human immunodeficiency virus among blood donors in ethiopia: a systematic review and meta-analysis |
publisher |
BMC |
series |
BMC Infectious Diseases |
issn |
1471-2334 |
publishDate |
2019-05-01 |
description |
Abstract Background Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficiency virus (HIV) is one of the major public health problems associated with blood transfusion. The objective of this systematic review and meta-analysis is to estimate seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia. Methods Studies on the prevalence of human immunodeficiency virus among blood donors published until 2017 were accessed by conducting a detailed search on PubMed, Cochrane Library, Google Scholar, EMBASE and CINAHL databases using the keywords:-“Seroprevalence” AND “trend” AND “HIV” OR “human” AND “immunodeficiency” AND “virus” OR “human immunodeficiency virus” AND “blood donors” OR “blood donors” OR “Ethiopia”. The quality of each article was assessed using a modified version of the Newcastle-Ottawa Scale. Meta-analysis was carried out using a random-effects method. All statistical analyses were done using STATA version 11 software. Result The estimated pooled seroprevalence of human immunodeficiency virus among blood donors in Ethiopia was 2.69% (95% CI (1.79–3.58%)). The overall seroprevalence of human immunodeficiency virus infection showed a significant decline trend from 2004 to 2016. Conclusion The overall seroprevalence of human immunodeficiency virus among blood donors in Ethiopia was high. Routine screening of donor blood for transfusion-transmissible infections is essential for ensuring the safety of blood transfusion. |
topic |
Blood donor Human immunodeficiency virus Seroprevalence Ethiopia |
url |
http://link.springer.com/article/10.1186/s12879-019-4012-5 |
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