Genomic amplification of <it>BCR/ABL1 </it>and a region downstream of <it>ABL1 </it>in chronic myeloid leukaemia: a FISH mapping study of CML patients and cell lines

<p>Abstract</p> <p>Background</p> <p>Chronic myeloid leukaemia (CML) is characterized by the expression of the <it>BCR/ABL1 </it>fusion gene, a constitutively activated tyrosine kinase that commonly results from the formation of the Philadelphia (Ph) chromos...

Full description

Bibliographic Details
Main Authors: Virgili Anna, Nacheva Elisabeth P
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cytogenetics
Online Access:http://www.molecularcytogenetics.org/content/3/1/15