Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis
Purpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected r...
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doaj-6436aaad279240ecad383172ba2672172020-11-24T21:28:50ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/89314308931430Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and PrognosisYoav Y. Pikkel0Daniel Krebs1Vadim Igal2Adi Sharabi-Nov3Irena Epstein4Joseph Pikkel5Carmel Medical Center, Haifa, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelTel Hai Academic College, Kiryat Shmona, IsraelOphthalmology Department, Ziv Medical Center, Safed, IsraelFaculty of Medicine, Bar-Ilan University, Safed, IsraelPurpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected regarding the retinal nerve fiber layer (RNFL), visual field (VF), line of treatment (LOT) of glaucoma, and all the data needed to accurately calculate CHA2DS2-VASc score for each patient. Results. Sixty-seven patients were included in the statistical analysis. The mean age was 72.5 years. The mean CHA2DS2-VASc score was 3.27 + −1.7. Positive Pearson’s correlation coefficients were found for LOT and CHA2DS2-VASc score, 0.35, and for RNFL grade and CHA2DS2-VASc score, 0.37. The correlation was negative for RNFL width and CHA2DS2-VASc score, −0.35. Conclusions. CHA2DS2-VASc score was shown to be correlated with glaucoma. This correlation was manifested positively by the LOT needed to stop glaucoma progression, with higher CHA2DS2-VASc scores correlated with more aggressive treatment. Since glaucoma is a disease with a progressing nature, it is important to treat patients aggressively on one hand, while offering the most benign treatment as possible on the other hand. Modification of the CHA2DS2-VASc score could achieve an even higher correlation.http://dx.doi.org/10.1155/2018/8931430 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yoav Y. Pikkel Daniel Krebs Vadim Igal Adi Sharabi-Nov Irena Epstein Joseph Pikkel |
spellingShingle |
Yoav Y. Pikkel Daniel Krebs Vadim Igal Adi Sharabi-Nov Irena Epstein Joseph Pikkel Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis Journal of Ophthalmology |
author_facet |
Yoav Y. Pikkel Daniel Krebs Vadim Igal Adi Sharabi-Nov Irena Epstein Joseph Pikkel |
author_sort |
Yoav Y. Pikkel |
title |
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis |
title_short |
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis |
title_full |
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis |
title_fullStr |
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis |
title_full_unstemmed |
Correlation between CHA2DS2-VASc Score and Glaucoma Treatment and Prognosis |
title_sort |
correlation between cha2ds2-vasc score and glaucoma treatment and prognosis |
publisher |
Hindawi Limited |
series |
Journal of Ophthalmology |
issn |
2090-004X 2090-0058 |
publishDate |
2018-01-01 |
description |
Purpose. To find if CHA2DS2-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG). Patients and methods. A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected regarding the retinal nerve fiber layer (RNFL), visual field (VF), line of treatment (LOT) of glaucoma, and all the data needed to accurately calculate CHA2DS2-VASc score for each patient. Results. Sixty-seven patients were included in the statistical analysis. The mean age was 72.5 years. The mean CHA2DS2-VASc score was 3.27 + −1.7. Positive Pearson’s correlation coefficients were found for LOT and CHA2DS2-VASc score, 0.35, and for RNFL grade and CHA2DS2-VASc score, 0.37. The correlation was negative for RNFL width and CHA2DS2-VASc score, −0.35. Conclusions. CHA2DS2-VASc score was shown to be correlated with glaucoma. This correlation was manifested positively by the LOT needed to stop glaucoma progression, with higher CHA2DS2-VASc scores correlated with more aggressive treatment. Since glaucoma is a disease with a progressing nature, it is important to treat patients aggressively on one hand, while offering the most benign treatment as possible on the other hand. Modification of the CHA2DS2-VASc score could achieve an even higher correlation. |
url |
http://dx.doi.org/10.1155/2018/8931430 |
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