Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins.

BACKGROUND:The entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes. The initial interaction between microbes and mucins is an important step for microbial path...

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Bibliographic Details
Main Authors: Radhakrishnan Prakash, Subramaniya Bharathi Raja, Halagowder Devaraj, Sivasitambaram Niranjali Devaraj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22073249/pdf/?tool=EBI