Differential diagnosis of adrenal gland tumor: rare case report

• Main Authors: Natalia I. Volkova, Liliya A. Ganenko, Vladimir Y. Mazhuhin, Aleksej N. Shevchenko
• Format: Article
• Language: Russian
• Published: Endocrinology Research Centre 2018-12-01
• Series: Эндокринная хирургия
• Subjects: adrenal incidentaloma; pheochromocytoma; adrenocortical carcinomas; case report
• Online Access: https://surg-endojournals.ru/serg/article/viewFile/10033/pdf
• ISSN: 2306-3513; 2310-3965

With the advent of high-resolution research methods (CT, MRI), randomly detectable formations in the adrenal glands became a clinical problem. The incidence of incidental adrenal glands varies between studies. So, according to the latest data, IN is detected in about 4-5% of patients who underwent radiological imaging. A clinical observation of a 39-year-old patient with complaints of persistent increase in blood pressure is presented. In the course of a routine ultrasound of the kidneys, the formation of a left adrenal gland was revealed. According to the data of the subsequent examination (adrenal SCT with contrast, determination of the hormonal profile), adrenocortical cancer, a glucocorticoid producing, was diagnosed. The patient underwent surgical treatment in the volume of left laparoscopic adrenalectomy. However, according to the results of a postoperative histological and immunohistochemical study, pheochromocytoma was diagnosed. The patient was discharged in satisfactory condition under the supervision of an endocrinologist and a surgeon. This clinical observation demonstrates that the ideal diagnostic approaches for differential diagnosis of IN have not yet been developed. Therefore, the continuation of research aimed at improving the diagnostic algorithm, which makes it possible to more accurately determine the morphological nature of education and its hormonal activity at the preoperative stage, is relevant both in scientific and in practical terms.