The Stimulatory Effect of MIP-1α on the Gene Transduction Efficacy of Cord Blood CD34+ Cells by a Pseudotype Retroviral Vector
"nIntroduction: Hematopoietic stem cells are always in a quiescence state. Since they need retroviral transduction to infect dividing cells, they are resistant to retrovirus transduction. They need to be pre-stimulated by a cytokine cocktail. For proliferation without maturation, we suggest...
Main Authors: | Kamran Alimoghaddam, L Moezzi, Hamid Ghaffari, Alireza Arjmand, P Ghodsi, Bahram Chahardouli, S Shahrokhi, Ardeshir Ghavamzadeh |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2009-04-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
Subjects: | |
Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16092.pdf&manuscript_id=16092 |
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