Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study

Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study

Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication...

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Bibliographic Details
Main Authors: Hanneke N. G. Oude Elberink, Mathilde Jalving, Hilda Dijkstra, Annick A. J. M. van de Ven
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical and Translational Allergy
Subjects:
Carboplatin
Desensitisation
Drug hypersensitivity
Omalizumab
Online Access:http://link.springer.com/article/10.1186/s13601-020-0309-0
Description
Summary:Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.
ISSN:2045-7022

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