Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study

Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication...

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Main Authors:	Hanneke N. G. Oude Elberink, Mathilde Jalving, Hilda Dijkstra, Annick A. J. M. van de Ven
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Clinical and Translational Allergy
Subjects:	Carboplatin Desensitisation Drug hypersensitivity Omalizumab
Online Access:	http://link.springer.com/article/10.1186/s13601-020-0309-0

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spelling	doaj-646b8687cf6d4079a25ba15fd132420f2021-09-02T12:17:58ZengWileyClinical and Translational Allergy2045-70222020-01-011011510.1186/s13601-020-0309-0Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case studyHanneke N. G. Oude Elberink0Mathilde Jalving1Hilda Dijkstra2Annick A. J. M. van de Ven3Department of Allergology and Internal Medicine, Internal address code AA21, University Medical Center GroningenDepartment of Allergology and Internal Medicine, Internal address code AA21, University Medical Center GroningenDepartment of Allergology and Internal Medicine, Internal address code AA21, University Medical Center GroningenDepartment of Allergology and Internal Medicine, Internal address code AA21, University Medical Center GroningenAbstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.http://link.springer.com/article/10.1186/s13601-020-0309-0CarboplatinDesensitisationDrug hypersensitivityOmalizumab
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hanneke N. G. Oude Elberink Mathilde Jalving Hilda Dijkstra Annick A. J. M. van de Ven
spellingShingle	Hanneke N. G. Oude Elberink Mathilde Jalving Hilda Dijkstra Annick A. J. M. van de Ven Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study Clinical and Translational Allergy Carboplatin Desensitisation Drug hypersensitivity Omalizumab
author_facet	Hanneke N. G. Oude Elberink Mathilde Jalving Hilda Dijkstra Annick A. J. M. van de Ven
author_sort	Hanneke N. G. Oude Elberink
title	Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
title_short	Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
title_full	Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
title_fullStr	Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
title_full_unstemmed	Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
title_sort	modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
publisher	Wiley
series	Clinical and Translational Allergy
issn	2045-7022
publishDate	2020-01-01
description	Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.
topic	Carboplatin Desensitisation Drug hypersensitivity Omalizumab
url	http://link.springer.com/article/10.1186/s13601-020-0309-0
work_keys_str_mv	AT hannekengoudeelberink modifiedprotocolofomalizumabtreatmenttopreventcarboplatininduceddrughypersensitivityreactionsacasestudy AT mathildejalving modifiedprotocolofomalizumabtreatmenttopreventcarboplatininduceddrughypersensitivityreactionsacasestudy AT hildadijkstra modifiedprotocolofomalizumabtreatmenttopreventcarboplatininduceddrughypersensitivityreactionsacasestudy AT annickajmvandeven modifiedprotocolofomalizumabtreatmenttopreventcarboplatininduceddrughypersensitivityreactionsacasestudy
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Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study

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