Immunomodulation by IVIg and the role of Fc-gamma receptors: classic mechanisms of action after all?

Intravenous IgG (IVIg) contains polyclonal IgG from thousands of donors. It is administered at a low dose at regular intervals as antibody replacement therapy and at a higher dose as immunomodulatory treatment in various auto-immune or auto-inflammatory diseases. The working mechanism of immunomodul...

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Bibliographic Details
Main Authors: Sietse Quirijn Nagelkerke, Taco Willem Kuijpers
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
IgG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00674/full

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