The Genetic Mutation of <i>ANO5</i> in Rabbits Recapitulates Human Cardiomyopathy

The Genetic Mutation of <i>ANO5</i> in Rabbits Recapitulates Human Cardiomyopathy

The limb girdle muscular dystrophy type 2L (LGMD2L) is caused by mutations of the <i>ANO5</i> gene in humans which encodes a 913 amino-acid integral membrane protein. Although cardiomyopathy has been reported in patients with an <i>ANO5</i> mutation, the <i>ANO5</i&g...

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Bibliographic Details
Main Authors: Tingting Sui, Hongwu Yao, Tao Zhang, Jinze Li, Liangxue Lai, Zhanjun Li
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Applied Sciences
Subjects:
CRISPR/Cas9
anoctamin 5
cardiomyopathy
rabbit
Online Access:https://www.mdpi.com/2076-3417/10/14/4976

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https://www.mdpi.com/2076-3417/10/14/4976

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