Guided web-based treatment program for reducing cannabis use: a randomized controlled trial
Abstract Background The aim of this study was to investigate the effects of a web-based treatment program with therapist guidance for adults and adolescents with regular cannabis use from the general population. Methods A double blinded randomized controlled trial with a parallel group design was co...
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doaj-64850e874bc54c2aa498e28be31d452f2020-11-25T03:08:48ZengBMCAddiction Science & Clinical Practice1940-06402020-02-0115111310.1186/s13722-020-00185-8Guided web-based treatment program for reducing cannabis use: a randomized controlled trialKristina Sinadinovic0Magnus Johansson1Ann-Sofie Johansson2Thomas Lundqvist3Philip Lindner4Ulric Hermansson5Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region StockholmDepartment of Global Public Health, Karolinska InstitutetStockholm Center for Dependency Disorders, Stockholm Health Care Services, Region StockholmDepartment of Psychology, Lund UniversityCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region StockholmCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region StockholmAbstract Background The aim of this study was to investigate the effects of a web-based treatment program with therapist guidance for adults and adolescents with regular cannabis use from the general population. Methods A double blinded randomized controlled trial with a parallel group design was conducted (intervention group n = 151, wait-list control group n = 152). Follow-up 12 weeks from treatment commencement of a 13-module intervention. The primary outcome was frequency of cannabis use. Time by group interaction effects were modeled using generalized estimated equations and the instrumental variable approach was used to estimate the effect of intervention adherence. Results At follow-up, the intention to treat (ITT) analyses did not show any significant time by group effects. A significant association between intervention adherence and scores on the cannabis abuse screening test (CAST) was found. Secondary analysis excluding participants who had received other professional help revealed time by group effects for secondary outcomes gram cannabis consumed past week, number of dependency criteria and CAST score. Due to methodological limitations, these latter results should be interpreted with caution. Conclusions In this study we did not find a web-based treatment program with therapist guidance to be more effective than a waiting-list in reducing frequency of cannabis use. Trial registration The trial was pre-registered at ClinicalTrials.gov (NCT02408640) April 3, 2015http://link.springer.com/article/10.1186/s13722-020-00185-8CannabisWeb-based treatment with therapist guidanceCognitive behavioral treatmenteHealthRandomized controlled trial |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kristina Sinadinovic Magnus Johansson Ann-Sofie Johansson Thomas Lundqvist Philip Lindner Ulric Hermansson |
spellingShingle |
Kristina Sinadinovic Magnus Johansson Ann-Sofie Johansson Thomas Lundqvist Philip Lindner Ulric Hermansson Guided web-based treatment program for reducing cannabis use: a randomized controlled trial Addiction Science & Clinical Practice Cannabis Web-based treatment with therapist guidance Cognitive behavioral treatment eHealth Randomized controlled trial |
author_facet |
Kristina Sinadinovic Magnus Johansson Ann-Sofie Johansson Thomas Lundqvist Philip Lindner Ulric Hermansson |
author_sort |
Kristina Sinadinovic |
title |
Guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
title_short |
Guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
title_full |
Guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
title_fullStr |
Guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
title_full_unstemmed |
Guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
title_sort |
guided web-based treatment program for reducing cannabis use: a randomized controlled trial |
publisher |
BMC |
series |
Addiction Science & Clinical Practice |
issn |
1940-0640 |
publishDate |
2020-02-01 |
description |
Abstract Background The aim of this study was to investigate the effects of a web-based treatment program with therapist guidance for adults and adolescents with regular cannabis use from the general population. Methods A double blinded randomized controlled trial with a parallel group design was conducted (intervention group n = 151, wait-list control group n = 152). Follow-up 12 weeks from treatment commencement of a 13-module intervention. The primary outcome was frequency of cannabis use. Time by group interaction effects were modeled using generalized estimated equations and the instrumental variable approach was used to estimate the effect of intervention adherence. Results At follow-up, the intention to treat (ITT) analyses did not show any significant time by group effects. A significant association between intervention adherence and scores on the cannabis abuse screening test (CAST) was found. Secondary analysis excluding participants who had received other professional help revealed time by group effects for secondary outcomes gram cannabis consumed past week, number of dependency criteria and CAST score. Due to methodological limitations, these latter results should be interpreted with caution. Conclusions In this study we did not find a web-based treatment program with therapist guidance to be more effective than a waiting-list in reducing frequency of cannabis use. Trial registration The trial was pre-registered at ClinicalTrials.gov (NCT02408640) April 3, 2015 |
topic |
Cannabis Web-based treatment with therapist guidance Cognitive behavioral treatment eHealth Randomized controlled trial |
url |
http://link.springer.com/article/10.1186/s13722-020-00185-8 |
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