Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications

Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications

Niacin (also known as “vitamin B<sub>3</sub>„ or “vitamin PP„) includes two vitamers (nicotinic acid and nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NAD...

Full description

Bibliographic Details
Main Authors:	Valeria Gasperi, Matteo Sibilano, Isabella Savini, Maria Valeria Catani
Format:	Article
Language:	English
Published:	MDPI AG 2019-02-01
Series:	International Journal of Molecular Sciences
Subjects:	central nervous system diet NAD(P) neurodegenerative diseases niacin nicotinamide nicotinic acid vitamin B<sub>3</sub>
Online Access:	https://www.mdpi.com/1422-0067/20/4/974

Similar Items

Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Lonza Benelux BV
by: EFSA Panel on Additives and Products or Substances used in Animal Feed
Published: (2012-07-01)

Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Vertellus Specialties Belgium BV
by: EFSA Panel on Additives and Products or Substances used in Animal Feed
Published: (2012-07-01)

Scientific Opinion on Dietary Reference Values for niacin
by: EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
Published: (2014-07-01)

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
by: Antonio Davila, et al.
Published: (2018-06-01)

Determination of niacin profiles in some animal and plant based foods by high performance liquid chromatography: association with healthy nutrition
by: Jale Çatak
Published: (2019-05-01)

Scientific Opinion on the safety and efficacy of niacin (nicotinamide) as a feed additive for all animal species based on a dossier submitted by EUROPE-ASIA Import Export GmbH
by: EFSA Panel on Additives and Products or Substances used in Animal Feed
Published: (2012-07-01)

Effect of Nicotinic Acid (Niacin) on Body Weight in New Zealand White Rabbits on Atherogenic Diet
by: Naheed Kausar
Published: (2012-12-01)

Life-Threatening Adverse Reaction after Self-Initiated, Off-Label Use of High Dose Nicotinamide for the Treatment of Friedreich’s Ataxia
by: Nicolas Garin, et al.
Published: (2015-06-01)

Structural and Functional Characterization of NadR from <i>Lactococcus lactis</i>
by: Artem Stetsenko, et al.
Published: (2020-04-01)

Farmacologia da niacina ou ácido nicotínico Pharmacology of niacin or nicotinic acid
by: Raul D. Santos
Published: (2005-10-01)

Lipid profiles of rats fed with diets supplemented with vitamins niacin and pyridoxine
by: Magna Glória Lameiro, et al.
Published: (2012-04-01)

Lipid profiles of rats fed with diets supplemented with vitamins niacin and pyridoxine
by: Magna da Glória Lameiro, et al.
Published: (2012-04-01)

Niacin Ameliorates Neuro-Inflammation in Parkinson’s Disease via GPR109A
by: Banabihari Giri, et al.
Published: (2019-09-01)

Niacin-mediated Gene Expression and Role of NiaR as a Transcriptional Repressor of niaX, nadC, and pnuC in Streptococcus pneumoniae
by: Muhammad Afzal, et al.
Published: (2017-03-01)

Safety of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of nicotinamide from this source, in the context of Directive 2002/46/EC
by: EFSA Panel on Nutrition, Novel foods and Food allergens (NDA), et al.
Published: (2019-08-01)

Identification et caractérisation de la nicotinamide phosphoribosyltransférase, une enzyme impliquée dans la biosynthèse du NAD
by: Rongvaux, Anthony
Published: (2004)

Cellular NAD Status as a Regulator of Skin Photodamage
by: Benavente, Claudia
Published: (2007)

Biomimetic thiamine- and niacin-decorated liposomes for enhanced oral delivery of insulin
by: Haisheng He, et al.
Published: (2018-01-01)

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+
by: Ross Grant, et al.
Published: (2019-09-01)

Effects of Formulation Design on Niacin Therapeutics: Mechanism of Action, Metabolism, and Drug Delivery
by: Cooper, David L., et al.
Published: (2015)

Effect of Niacin on Side Effects of Bleomycin in Patients under Chemotherapy in Khansari Hospital of Arak
by: Zhila Mohseni, et al.
Published: (2018-08-01)

Effect of niacin monotherapy on high density lipoprotein composition and function
by: Scott M. Gordon, et al.
Published: (2020-08-01)

Factors affecting storage stability of vitamin A, riboflavin and niacin in a broiler diet premix
by: Zhuge, Qiang.
Published: (2015)

The effects of niacin deficiency on phagocytosis and susceptibility to infection
by: Siebeling, Ronald Jon, 1937-
Published: (1962)

Influence of niacin administration on lipid peroxidation in cows in early lactation
by: Hristovska Talija, et al.
Published: (2018-01-01)

Dietary Niacin Supplementation Suppressed Hepatic Lipid Accumulation in Rabbits
by: Lei Liu, et al.
Published: (2016-12-01)

Niacin alters the ruminal microbial composition of cattle under high-concentrate condition
by: Dan Luo, et al.
Published: (2017-06-01)

The Biochemical Pathways of Nicotinamide-Derived Pyridones
by: Faisal Hayat, et al.
Published: (2021-01-01)

Clinical Evidence for Targeting NAD Therapeutically
by: Dina Radenkovic, et al.
Published: (2020-09-01)

A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects
by: Takashi K. Ito, et al.
Published: (2021-01-01)

A nonrandomized study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects
by: Takashi K. Ito, et al.
Published: (2020-01-01)

NADomics: Measuring NAD<sup>+</sup> and Related Metabolites Using Liquid Chromatography Mass Spectrometry
by: Nady Braidy, et al.
Published: (2021-05-01)

A comparative study on the effects of niacin plus atorvastatin with that of fenofibrate plus atorvastatin in dyslipidemia
by: Salim Ahmed, et al.
Published: (2008-06-01)

A comparative study on the effects of niacin plus atorvastatin with that of fenofibrate plus atorvastatin in dyslipidemia
by: Selim Ahmed, et al.
Published: (2008-04-01)

Total Nicotinic Acid Metabolism of Young College Women on Self-Selected Diets
by: Fuller, Golda Faye Graham
Published: (1952)

The Absence of Adiponectin Alters Niacin’s Effects on Adipose Tissue Inflammation in Mice
by: Emily C. Graff, et al.
Published: (2020-08-01)

Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor
by: Adepu, K.K, et al.
Published: (2021)

Minireview Exploring the Biological Cycle of Vitamin B3 and Its Influence on Oxidative Stress: Further Molecular and Clinical Aspects
by: Bogdan Doroftei, et al.
Published: (2020-07-01)

Bioavailability of niacin from tuna fish, peanut butter and whole wheat bread
by: Wei, Ien-lan
Published: (2012)

Niacin Inhibits Apoptosis and Rescues Premature Ovarian Failure
by: Shufang Wang, et al.
Published: (2018-11-01)