High content drug screening for Fanconi anemia therapeutics

High content drug screening for Fanconi anemia therapeutics

Abstract Background Fanconi anemia is a rare disease clinically characterized by malformations, bone marrow failure and an increased risk of solid tumors and hematologic malignancies. The only therapies available are hematopoietic stem cell transplantation for bone marrow failure or leukemia, and su...

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Bibliographic Details
Main Authors: Helena Montanuy, Cristina Camps-Fajol, Jordi Carreras-Puigvert, Maria Häggblad, Bo Lundgren, Miriam Aza-Carmona, Thomas Helleday, Jordi Minguillón, Jordi Surrallés
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Fanconi anemia
High content screening
Drug repositioning
Cell-based assay
Online Access:http://link.springer.com/article/10.1186/s13023-020-01437-1

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