The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb.

The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb.

The type 3 adenylyl cyclase (AC3) is localized to olfactory cilia in the main olfactory epithelium (MOE) and primary cilia in the adult mouse brain. Although AC3 has been strongly implicated in odor perception and olfactory sensory neuron (OSN) targeting, its role in granule cells (GCs), the most ab...

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Bibliographic Details
Main Authors: Jie Luo, Xuanmao Chen, Yung-Wei Pan, Song Lu, Zhengui Xia, Daniel R Storm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373939?pdf=render

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