Environmental exposure to non-persistent endocrine disrupting chemicals and semen quality: An overview of the current epidemiological evidence
Some of the recent publications have reported a decline in semen quality in the last few decades. This phenomenon is associated with environmental factors, particularly with exposure to endocrine disrupting chemicals (EDCs). The aim of this publication is to critically review the literature on expos...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nofer Institute of Occupational Medicine
2018-07-01
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Series: | International Journal of Occupational Medicine and Environmental Health |
Subjects: | |
Online Access: | http://www.journalssystem.com/ijomeh/Environmental-exposure-to-non-persistent-endocrine-disrupting-chemicals-and-semen,76451,0,2.html |
Summary: | Some of the recent publications have reported a decline in semen quality in the last few decades. This phenomenon is associated
with environmental factors, particularly with exposure to endocrine disrupting chemicals (EDCs). The aim of this publication
is to critically review the literature on exposure to the following 6 ubiquitous environmental non-persistent EDCs:
bisphenol A, triclosan, parabens, synthetic pyrethroids, organophosphate pesticides and phthalates, and on their influence
on semen quality measured as sperm concentration, sperm volume, total sperm count, motility, total motile count, morphology,
sperm motion, sperm DNA damage (comet extent, tail length, tail distributed moment, percent of DNA located in
the tail (tail%), DNA fragmentation index, high DNA stainability, X:Y ratio and aneuploidy. Several electronic databases
were systematically searched until 31 August 2016. Studies were qualified for the review if they: linked environmental exposure
to non-persistent EDCs to semen quality outcomes, were published in English after 2006 (and, in the case of phthalates,
if they were published after 2009) and were conducted in the case of humans. Out of the 970 references, 45 articles
were included in the review. This review adds to the body of evidence that exposure to non-persistent EDCs may affect
semen quality parameters and decrease semen quality. Int J Occup Med Environ Health 2018;31(4):377–414 |
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ISSN: | 1232-1087 1896-494X |