Transcription of AAT•ATT triplet repeats in Escherichia coli is silenced by H-NS and IS1E transposition.

Transcription of AAT•ATT triplet repeats in Escherichia coli is silenced by H-NS and IS1E transposition.

The trinucleotide repeats AAT•ATT are simple DNA sequences that potentially form different types of non-B DNA secondary structures and cause genomic instabilities in vivo.The molecular mechanism underlying the maintenance of a 24-triplet AAT•ATT repeat was examined in E. coli by cloning the repeats...

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Bibliographic Details
Main Authors: Xuefeng Pan, Yuanhong Liao, Yunmeng Liu, Peng Chang, Lingni Liao, Li Yang, Hongquan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3000339?pdf=render

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