HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission

HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission

Abscission is the final step of cell division, mediating the physical separation of the two daughter cells. A key player in this process is the microtubule-severing enzyme spastin that localizes at the midbody where its activity is crucial to cut microtubules and culminate the cytokinesis. Recently,...

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Bibliographic Details
Main Authors: Alessandra Pisciottani, Loredana Biancolillo, Manuela Ferrara, Davide Valente, Francesca Sardina, Laura Monteonofrio, Serena Camerini, Marco Crescenzi, Silvia Soddu, Cinzia Rinaldo
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
HIPK2
spastin
abscission
midbody
phosphorylation
Online Access:https://www.mdpi.com/2073-4409/8/7/684

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