Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome
Summary Objective: The aim of this study was to evaluate the effect of rhubarb on extravascular lung water (EVLW) in patients with acute respiratory distress syndrome (ARDS). Method: A total of 80 patients with ARDS were randomly divided into a treatment group (40 cases) and control group (40 case...
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doaj-6532d879d1124c63b8258fa0207181c62020-11-24T22:52:14ZengAssociação Médica BrasileiraRevista da Associação Médica Brasileira1806-928263543544010.1590/1806-9282.63.05.435S0104-42302017000500435Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndromeJianxin HeXiaoshui SiMingxia JiJing HuangWenjuan ZhengJiao WangJunfeng WangLijun ZhuSummary Objective: The aim of this study was to evaluate the effect of rhubarb on extravascular lung water (EVLW) in patients with acute respiratory distress syndrome (ARDS). Method: A total of 80 patients with ARDS were randomly divided into a treatment group (40 cases) and control group (40 cases). Patients in the treatment group received rhubarb (30.0 g/d) and patients in the control group received conventional therapy for seven consecutive days. Extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) were determined using pulse contour cardiac output (PiCCO) technology, and the oxygenation index was measured by blood gas analysis at baseline and on days 3, 5 and 7 after treatment. Results: The oxygenation index was higher and the levels of EVLWI and PVPI were lower after treatment in the two groups; however, these indexes showed significant differences on the 5th and 7th days after rhubarb treatment compared with the results in the control group (p<0.05). Conclusion: Rhubarb can decrease EVLWI and PVPI, and improve oxygenation in patients with ARDS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000500435&lng=en&tlng=enrhubarbARDSEVLWIoxygenation index |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jianxin He Xiaoshui Si Mingxia Ji Jing Huang Wenjuan Zheng Jiao Wang Junfeng Wang Lijun Zhu |
spellingShingle |
Jianxin He Xiaoshui Si Mingxia Ji Jing Huang Wenjuan Zheng Jiao Wang Junfeng Wang Lijun Zhu Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome Revista da Associação Médica Brasileira rhubarb ARDS EVLWI oxygenation index |
author_facet |
Jianxin He Xiaoshui Si Mingxia Ji Jing Huang Wenjuan Zheng Jiao Wang Junfeng Wang Lijun Zhu |
author_sort |
Jianxin He |
title |
Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
title_short |
Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
title_full |
Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
title_fullStr |
Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
title_full_unstemmed |
Effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
title_sort |
effect of rhubarb on extravascular lung water in patients with acute respiratory distress syndrome |
publisher |
Associação Médica Brasileira |
series |
Revista da Associação Médica Brasileira |
issn |
1806-9282 |
description |
Summary Objective: The aim of this study was to evaluate the effect of rhubarb on extravascular lung water (EVLW) in patients with acute respiratory distress syndrome (ARDS). Method: A total of 80 patients with ARDS were randomly divided into a treatment group (40 cases) and control group (40 cases). Patients in the treatment group received rhubarb (30.0 g/d) and patients in the control group received conventional therapy for seven consecutive days. Extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) were determined using pulse contour cardiac output (PiCCO) technology, and the oxygenation index was measured by blood gas analysis at baseline and on days 3, 5 and 7 after treatment. Results: The oxygenation index was higher and the levels of EVLWI and PVPI were lower after treatment in the two groups; however, these indexes showed significant differences on the 5th and 7th days after rhubarb treatment compared with the results in the control group (p<0.05). Conclusion: Rhubarb can decrease EVLWI and PVPI, and improve oxygenation in patients with ARDS. |
topic |
rhubarb ARDS EVLWI oxygenation index |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000500435&lng=en&tlng=en |
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