Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation
Background: The abundance of energy metabolites is intimately interconnected with the activity of chromatin-modifying enzymes in order to guarantee the finely tuned modulation of gene expression in response to cellular energetic status. Metabolism-induced epigenetic gene regulation is a key molecula...
Main Authors: | Annalisa Roberti, Agustín F. Fernández, Mario F. Fraga |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Molecular Metabolism |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877821000053 |
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