In vitro antioxidant activity and Content of compounds from Curculigo orchioides rhizome

• Main Authors: Le Trung Hieu, Le Lam Son, Nguyen Thi Nguyet, Nguyen Minh Nhung, Ho Xuan Anh Vu, Nguyen Quang Man, Le Thuy Trang, Tran Thanh Minh, Tran Thi Van Thi
• Format: Article
• Language: English
• Published: HUJOS 2020-06-01
• Series: Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên
• Subjects: curculigo orchioides; antioxidant activity; polysaccharide; saponin – triterpenoids; total phenolic content; total flavonoid content.
• Online Access: http://jos.hueuni.edu.vn/index.php/HUJOS-NS/article/view/5749
• ISSN: 1859-1388; 2615-9678

Curculigo orchioides Gaertn. is used in traditional medicine in Vietnam. Its antioxidant potential was evaluated through DPPH radical scavenging and the total antioxidant capacity method. The data resulted from DPPH radical scavenging activity indicate that Curculigo orchioides display high activity with a low IC50 value (22.78μg/mL), approximately 1.5 times less than that of curcumin (34.34 μg/mL). The total antioxidant capacity of the extract is equivalent to 132.48 ± 1.48 mg GA/g or 264.45 ± 2.34 μmol AS/g. The composition of Curculigo orchioides, including the total phenolic, total flavonoid, polysaccharides, and triterpenoid saponins, was examined by using the colorimetric method with reagents, and their quantity is equivalent to 196.24 ± 1.45 mg GAE/g, 78.49 ± 1.78 mg QE/g, 4.34 ± 0.08 %, 47.60 ± 0.24 mg Rb1/g (Rb1: Gypenoside III), respectively. Specifically, the total triterpenoid saponins content of Curculigo orchioides has been reported for the first time.