Characterization of Solid-State Drug Polymorphs and Real-Time Evaluation of Crystallization Process Consistency by Near-Infrared Spectroscopy

Herein, we aimed to develop a strategy for evaluating the consistency of pharmaceutically important crystallization processes in real time, focusing on two typical cases of polymorphism. Theoretical analysis using a combination of 13C solid-state nuclear magnetic resonance spectroscopy with other po...

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Bibliographic Details
Main Authors: Shu-Ye Qi, Ye Tian, Wen-Bo Zou, Chang-Qin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00506/full

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