Temporal Bone Myeloid Sarcoma

Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disea...

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Bibliographic Details
Main Authors: Ki-Hong Chang, Dong-Kee Kim, Beom-Cho Jun, Yong-Soo Park
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2009-12-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Online Access:http://www.e-ceo.org/upload/pdf/ceo-2-198.pdf
Description
Summary:Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disease is difficult to diagnose when it presents with symptoms that mimic otomastoiditis. However, an early diagnosis is important in order to achieve complete remission of the disease. Magnetic resonance imaging of the temporal bone is useful for making the diagnosis of myeloid sarcoma, and especially to evaluate the extent of disease. High-dose radio- or chemotherapies are the first-line approaches and possibly the only approaches to achieve complete remission and to cure the disease. With the aim of improving our understanding of myeloid sarcoma in the temporal bone, the present report describes our experience with 5 such cases and we compare the clinical features of these 5 patients with those clinical features of patients who have metastatic lesions.
ISSN:1976-8710
2005-0720