Mechanisms of DNA Methyltransferase Recruitment in Mammals

DNA methylation is an essential epigenetic mark in mammals. The proper distribution of this mark depends on accurate deposition and maintenance mechanisms, and underpins its functional role. This, in turn, depends on the precise recruitment and activation of de novo and maintenance DNA methyltransfe...

Full description

Bibliographic Details
Main Authors: Marthe Laisné, Nikhil Gupta, Olivier Kirsh, Sriharsa Pradhan, Pierre-Antoine Defossez
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/9/12/617