Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?

Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to...

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Main Authors: Christina Fotopoulou, Ioana Braicu, Jalid Sehouli
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2012/238061
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spelling doaj-659c642e233147dcb6bec4f6dbe27d092020-11-24T22:30:42ZengHindawi LimitedObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/238061238061Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?Christina Fotopoulou0Ioana Braicu1Jalid Sehouli2Department of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyDepartment of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyDepartment of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyEpithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to the optimal therapeutic treatment strategies, gynecologic oncologists are being asked to incorporate into their decision-making processes the patients' wish for fertility preserving alternatives ideally without compromising oncologic safety. Nowadays, fertility-sparing surgery represents an effective alternative to conventional radical cytoreduction in younger women with early stages of the disease. As such, this paper considers indications for fertility sparing surgery in EOC, reflects on outcomes from the oncologic and reproductive data of the largest and most relevant series outcomes data, reporting on fertility sparing techniques in EOC, reviews medicamentous efforts to prevent chemotherapy induced gonadotoxicity, and discusses future aspects in the gynecologic cancer management.http://dx.doi.org/10.1155/2012/238061
collection DOAJ
language English
format Article
sources DOAJ
author Christina Fotopoulou
Ioana Braicu
Jalid Sehouli
spellingShingle Christina Fotopoulou
Ioana Braicu
Jalid Sehouli
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
Obstetrics and Gynecology International
author_facet Christina Fotopoulou
Ioana Braicu
Jalid Sehouli
author_sort Christina Fotopoulou
title Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
title_short Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
title_full Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
title_fullStr Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
title_full_unstemmed Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
title_sort fertility-sparing surgery in early epithelial ovarian cancer: a viable option?
publisher Hindawi Limited
series Obstetrics and Gynecology International
issn 1687-9589
1687-9597
publishDate 2012-01-01
description Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to the optimal therapeutic treatment strategies, gynecologic oncologists are being asked to incorporate into their decision-making processes the patients' wish for fertility preserving alternatives ideally without compromising oncologic safety. Nowadays, fertility-sparing surgery represents an effective alternative to conventional radical cytoreduction in younger women with early stages of the disease. As such, this paper considers indications for fertility sparing surgery in EOC, reflects on outcomes from the oncologic and reproductive data of the largest and most relevant series outcomes data, reporting on fertility sparing techniques in EOC, reviews medicamentous efforts to prevent chemotherapy induced gonadotoxicity, and discusses future aspects in the gynecologic cancer management.
url http://dx.doi.org/10.1155/2012/238061
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AT ioanabraicu fertilitysparingsurgeryinearlyepithelialovariancanceraviableoption
AT jalidsehouli fertilitysparingsurgeryinearlyepithelialovariancanceraviableoption
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