Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?
Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to...
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Online Access: | http://dx.doi.org/10.1155/2012/238061 |
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doaj-659c642e233147dcb6bec4f6dbe27d092020-11-24T22:30:42ZengHindawi LimitedObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/238061238061Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?Christina Fotopoulou0Ioana Braicu1Jalid Sehouli2Department of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyDepartment of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyDepartment of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charité University Hospital, 13353 Berlin, GermanyEpithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to the optimal therapeutic treatment strategies, gynecologic oncologists are being asked to incorporate into their decision-making processes the patients' wish for fertility preserving alternatives ideally without compromising oncologic safety. Nowadays, fertility-sparing surgery represents an effective alternative to conventional radical cytoreduction in younger women with early stages of the disease. As such, this paper considers indications for fertility sparing surgery in EOC, reflects on outcomes from the oncologic and reproductive data of the largest and most relevant series outcomes data, reporting on fertility sparing techniques in EOC, reviews medicamentous efforts to prevent chemotherapy induced gonadotoxicity, and discusses future aspects in the gynecologic cancer management.http://dx.doi.org/10.1155/2012/238061 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christina Fotopoulou Ioana Braicu Jalid Sehouli |
spellingShingle |
Christina Fotopoulou Ioana Braicu Jalid Sehouli Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? Obstetrics and Gynecology International |
author_facet |
Christina Fotopoulou Ioana Braicu Jalid Sehouli |
author_sort |
Christina Fotopoulou |
title |
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? |
title_short |
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? |
title_full |
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? |
title_fullStr |
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? |
title_full_unstemmed |
Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option? |
title_sort |
fertility-sparing surgery in early epithelial ovarian cancer: a viable option? |
publisher |
Hindawi Limited |
series |
Obstetrics and Gynecology International |
issn |
1687-9589 1687-9597 |
publishDate |
2012-01-01 |
description |
Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in major impacts on treatment management. Next to the optimal therapeutic treatment strategies, gynecologic oncologists are being asked to incorporate into their decision-making processes the patients' wish for fertility preserving alternatives ideally without compromising oncologic safety. Nowadays, fertility-sparing surgery represents an effective alternative to conventional radical cytoreduction in younger women with early stages of the disease. As such, this paper considers indications for fertility sparing surgery in EOC, reflects on outcomes from the oncologic and reproductive data of the largest and most relevant series outcomes data, reporting on fertility sparing techniques in EOC, reviews medicamentous efforts to prevent chemotherapy induced gonadotoxicity, and discusses future aspects in the gynecologic cancer management. |
url |
http://dx.doi.org/10.1155/2012/238061 |
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