Galectins as self/non-self recognition receptors in innate and adaptive immunity: An unresolved paradox

Galectins as self/non-self recognition receptors in innate and adaptive immunity: An unresolved paradox

Galectins are characterized by their binding affinity for ß-galactosides, a unique binding site sequence motif, and wide taxonomic distribution and structural conservation in vertebrates, invertebrates, protista, and fungi. Since their initial description, galectins were considered to bind...

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Bibliographic Details
Main Authors: Gerardo R. Vasta, Hafiz eAhmed, Mihai eNita-Lazar, Aditi eBanerjee, Marta ePasek, Surekha eShridhar, Prasun eGuha, José A Fernández-Robledo
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
C-type lectin
galectin
glycan ligands
microbial recognition
self/non-self recognition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00199/full

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