Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer

Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer

<p>Abstract</p> <p>Background</p> <p>Combination therapy of irinotecan, folinic acid (FA) and 5-fluorouracil (5-FU) has been proven to be highly effective for the treatment of metastatic colorectal cancer. However, in light of safety and efficacy concerns, the best comb...

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Bibliographic Details
Main Authors: Höhler Thomas, Klein O, Adami Bernd, Schroeder M, Hohl Herbert, Zanke Christiane, Siebler Jürgen, Steinmann Silke, Teufel Andreas, Galle Peter R, Heike Michael, Moehler Markus
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Cancer
Subjects:
irinotecan
5-fluorouracil
safety
metastatic colorectal cancer
neoadjuvant
Online Access:http://www.biomedcentral.com/1471-2407/4/38

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