Polyisobutylene—New Opportunities for Medical Applications

This paper presents the results of the first part of testing a novel electrospun fiber mat based on a unique macromolecule: polyisobutylene (PIB). A PIB-based compound containing zinc oxide (ZnO) was electrospun into self-supporting mats of 203.75 and 295.5 g/m<sup>2</sup> that were inve...

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Main Authors:	Dóra Barczikai, Judit Domokos, Dóra Szabó, Kristof Molnar, David Juriga, Eniko Krisch, Krisztina S. Nagy, Laszlo Kohidai, Carin A. Helfer, Angela Jedlovszky-Hajdu, Judit E. Puskas
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Molecules
Subjects:	polyisobutylene electrospinning fiber mat cell adhesion biofilm formation COVID mask
Online Access:	https://www.mdpi.com/1420-3049/26/17/5207

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spelling	doaj-65b27b3572614f23a24b59c68f4767052021-09-09T13:53:05ZengMDPI AGMolecules1420-30492021-08-01265207520710.3390/molecules26175207Polyisobutylene—New Opportunities for Medical ApplicationsDóra Barczikai0Judit Domokos1Dóra Szabó2Kristof Molnar3David Juriga4Eniko Krisch5Krisztina S. Nagy6Laszlo Kohidai7Carin A. Helfer8Angela Jedlovszky-Hajdu9Judit E. Puskas10Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryInstitute of Medical Microbiology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryInstitute of Medical Microbiology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryDepartment of Food, Agricultural and Biological Engineering, College of Food, Agricultural, and Environmental Sciences, The Ohio State University, 222 FABE, 1680 Madison Avenue, Wooster, OH 44691, USALaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryDepartment of Food, Agricultural and Biological Engineering, College of Food, Agricultural, and Environmental Sciences, The Ohio State University, 222 FABE, 1680 Madison Avenue, Wooster, OH 44691, USALaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryDepartment of Food, Agricultural and Biological Engineering, College of Food, Agricultural, and Environmental Sciences, The Ohio State University, 222 FABE, 1680 Madison Avenue, Wooster, OH 44691, USALaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Nagyvárad tér 4, H-1089 Budapest, HungaryDepartment of Food, Agricultural and Biological Engineering, College of Food, Agricultural, and Environmental Sciences, The Ohio State University, 222 FABE, 1680 Madison Avenue, Wooster, OH 44691, USAThis paper presents the results of the first part of testing a novel electrospun fiber mat based on a unique macromolecule: polyisobutylene (PIB). A PIB-based compound containing zinc oxide (ZnO) was electrospun into self-supporting mats of 203.75 and 295.5 g/m<sup>2</sup> that were investigated using a variety of techniques. The results show that the hydrophobic mats are not cytotoxic, resist fibroblast cell adhesion and biofilm formation and are comfortable and easy to breathe through for use as a mask. The mats show great promise for personal protective equipment and other applications.https://www.mdpi.com/1420-3049/26/17/5207polyisobutyleneelectrospinningfiber matcell adhesionbiofilm formationCOVID mask
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Dóra Barczikai Judit Domokos Dóra Szabó Kristof Molnar David Juriga Eniko Krisch Krisztina S. Nagy Laszlo Kohidai Carin A. Helfer Angela Jedlovszky-Hajdu Judit E. Puskas
spellingShingle	Dóra Barczikai Judit Domokos Dóra Szabó Kristof Molnar David Juriga Eniko Krisch Krisztina S. Nagy Laszlo Kohidai Carin A. Helfer Angela Jedlovszky-Hajdu Judit E. Puskas Polyisobutylene—New Opportunities for Medical Applications Molecules polyisobutylene electrospinning fiber mat cell adhesion biofilm formation COVID mask
author_facet	Dóra Barczikai Judit Domokos Dóra Szabó Kristof Molnar David Juriga Eniko Krisch Krisztina S. Nagy Laszlo Kohidai Carin A. Helfer Angela Jedlovszky-Hajdu Judit E. Puskas
author_sort	Dóra Barczikai
title	Polyisobutylene—New Opportunities for Medical Applications
title_short	Polyisobutylene—New Opportunities for Medical Applications
title_full	Polyisobutylene—New Opportunities for Medical Applications
title_fullStr	Polyisobutylene—New Opportunities for Medical Applications
title_full_unstemmed	Polyisobutylene—New Opportunities for Medical Applications
title_sort	polyisobutylene—new opportunities for medical applications
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2021-08-01
description	This paper presents the results of the first part of testing a novel electrospun fiber mat based on a unique macromolecule: polyisobutylene (PIB). A PIB-based compound containing zinc oxide (ZnO) was electrospun into self-supporting mats of 203.75 and 295.5 g/m<sup>2</sup> that were investigated using a variety of techniques. The results show that the hydrophobic mats are not cytotoxic, resist fibroblast cell adhesion and biofilm formation and are comfortable and easy to breathe through for use as a mask. The mats show great promise for personal protective equipment and other applications.
topic	polyisobutylene electrospinning fiber mat cell adhesion biofilm formation COVID mask
url	https://www.mdpi.com/1420-3049/26/17/5207
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Polyisobutylene—New Opportunities for Medical Applications

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