Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease in Kashi Region, Northwestern China

• Main Authors: Li L, Zhong X, Zheng A, JianKun C, Budukadeer AA, Aini P, Tuerxun M, Yasen M, Ma T, Ren J, Semaiti R, Xie C, Li F, Rexiati M, Tang L, Abudurexiti G, Zheng D, Li JQ
• Format: Article
• Language: English
• Published: Dove Medical Press 2021-03-01
• Series: International Journal of COPD
• Subjects: uyghur population; chronic obstructive pulmonary disease; prevalence; risk factors; epidemiology study
• Online Access: https://www.dovepress.com/prevalence-and-risk-factors-of-chronic-obstructive-pulmonary-disease-i-peer-reviewed-article-COPD

Li Li,1,* Xuemei Zhong,1,* Aifang Zheng,1 Chen JianKun,2,3 Ayiguzali A Budukadeer,1 Paierda Aini,1 Maimaitiaili Tuerxun,1 Mukeremu Yasen,1 Tao Ma,1 Jie Ren,1 Rukeyamu Semaiti,1 Chengxin Xie,1 Feifei Li,1 Mireban Rexiati,1 Lifeng Tang,1 Gulanbaier Abudurexiti,1 Dayong Zheng,1 Ji-Qiang Li1– 3 1Department of Respiratory and Critical Care Medicine, The First People’s Hospital of Kashi Prefecture, Kashi, Xinjiang, People’s Republic of China; 2The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 3The Third Comprehensive Department, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dayong ZhengDepartment of Respiratory and Critical Care Medicine, The First People’s Hospital of Kashi Prefecture, 120 Yingbin Road, Kashi City, Xinjiang, 844000, People’s Republic of ChinaTel [phone]Email [e-mail]-Qiang LiThe Second Clinical College, Guangzhou University of Chinese Medicine, 232 Waihuan East Road, Guangzhou University City, Panyu District of Guangzhou, Guangzhou, 510120, People’s Republic of ChinaTel [phone]Email [e-mail]: To investigate the prevalence and the risk factors of COPD in the Uyghur population in the Kashi region.Methods: From August 2018 to March 2019, we recruited participants of Uyghur ethnicity and aged ≥ 40 years old from the Kashi region using a combined cluster sampling and random sampling method. We collected potential risk factors using questionnaire, and conduced lung function using a portable pulmonary function instrument.Results: A total of 2963 participants were included in this analysis, of whom 1268 were males and 1695 were females. There were 504 participants with COPD, generating a prevalence of 17.01%. With the increase of age, the prevalence of COPD in different genders increased significantly. The results of different regions were χ2= 627.89, p < 0.01, indicating significant differences in the prevalence in different regions. Among them, based on the existing survey data, it is speculated that Shache county has the highest crude prevalence, but the sample size needs to be further expanded. The participants with high age, smoking, lower BMI, high waist circumference, systolic blood pressure, fried cooking and barbecue share more COPD than those who partake of fruits and vegetables in this study.Conclusion: The prevalence of COPD among the Uyghur population in the Kashi region is higher than the national rural average. Among them, high age, smoking, low BMI, high waist circumference, high systolic blood pressure, cooking methods that may be stir-fried and deep-fried barbecue are risk factors for COPD, and vegetable and fruit intake may be a protective factor for COPD.Keywords: Uyghur population, chronic obstructive pulmonary disease, prevalence, risk factors, epidemiology study