From Yeast to Mammals, the Nonsense-Mediated mRNA Decay as a Master Regulator of Long Non-Coding RNAs Functional Trajectory

From Yeast to Mammals, the Nonsense-Mediated mRNA Decay as a Master Regulator of Long Non-Coding RNAs Functional Trajectory

The Nonsense-Mediated mRNA Decay (NMD) has been classically viewed as a translation-dependent RNA surveillance pathway degrading aberrant mRNAs containing premature stop codons. However, it is now clear that mRNA quality control represents only one face of the multiple functions of NMD. Indeed, NMD...

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Bibliographic Details
Main Authors: Sara Andjus, Antonin Morillon, Maxime Wery
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Non-Coding RNA
Subjects:
nonsense-mediated mRNA decay
Upf1
lncRNA
translation
micropeptide
Online Access:https://www.mdpi.com/2311-553X/7/3/44

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