Effect of ulinastatin on post-operative blood loss and allogeneic transfusion in patients receiving cardiac surgery with cardiopulmonary bypass: a prospective randomized controlled study with 10-year follow-up

Effect of ulinastatin on post-operative blood loss and allogeneic transfusion in patients receiving cardiac surgery with cardiopulmonary bypass: a prospective randomized controlled study with 10-year follow-up

Abstract Background Major bleeding and allogeneic transfusion leads to negative outcomes in patients receiving cardiac surgery with cardiopulmonary bypass (CPB). Ulinastatin, a urine trypsin inhibitor, relieves systemic inflammation and improves coagulation profiles with however sparse evidence of i...

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Bibliographic Details
Main Authors: Peng Zhang, Hong Lv, Xia Qi, Wenjing Xiao, Qinghua Xue, Lei Zhang, Lihuan Li, Jia Shi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Ulinastatin
Tranexamic acid
Blood conservation
Cardiopulmonary bypass
Online Access:http://link.springer.com/article/10.1186/s13019-020-01144-9

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