Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage
Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and th...
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doaj-65c5c8c3da2e422381f3f821ae110a8d2020-11-24T22:02:23ZengMDPI AGMaterials1996-19442019-10-011220341310.3390/ma12203413ma12203413Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human CartilageAndreia Sofia Oliveira0Oumar Seidi1Nuno Ribeiro2Rogério Colaço3Ana Paula Serro4Centro de Química Estrutural (CQE), Instituto Superior Técnico-Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, PortugalInstitut Supérieur des BioSciences (ISBS), École Supérieure d’Ingénieurs de Paris-Est Créteil, 71 Rue Saint-Simon, 94000 Créteil, FranceCentro de Química Estrutural (CQE), Instituto Superior Técnico-Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, PortugalInstituto de Engenharia Mecânica Instituto Superior Técnico (IDMEC)-Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, PortugalCentro de Química Estrutural (CQE), Instituto Superior Técnico-Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, PortugalDesigning materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.https://www.mdpi.com/1996-1944/12/20/3413poly(vinyl alcohol) hydrogelfreeze-thawingcast-dryinghuman cartilagemechanical propertiestribological behavior |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andreia Sofia Oliveira Oumar Seidi Nuno Ribeiro Rogério Colaço Ana Paula Serro |
spellingShingle |
Andreia Sofia Oliveira Oumar Seidi Nuno Ribeiro Rogério Colaço Ana Paula Serro Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage Materials poly(vinyl alcohol) hydrogel freeze-thawing cast-drying human cartilage mechanical properties tribological behavior |
author_facet |
Andreia Sofia Oliveira Oumar Seidi Nuno Ribeiro Rogério Colaço Ana Paula Serro |
author_sort |
Andreia Sofia Oliveira |
title |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_short |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_full |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_fullStr |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_full_unstemmed |
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage |
title_sort |
tribomechanical comparison between pva hydrogels obtained using different processing conditions and human cartilage |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2019-10-01 |
description |
Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones. |
topic |
poly(vinyl alcohol) hydrogel freeze-thawing cast-drying human cartilage mechanical properties tribological behavior |
url |
https://www.mdpi.com/1996-1944/12/20/3413 |
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